Conference Proceedings

Seventh International Conference On Advances in Mechanical, Aeronautical and Production Techniques - MAPT 2017

The Exact Specification for Consumption of Blood-Pressure Regulating Drugs with a Numerical Model of Pulsatile Micropolar Fluid Flow in Elastic Vessel

Author(s) : H. ASKARIAN, S. GHOLAMREZAIE, S. MADDAH

Abstract

In the present paper, the problem of pulsatile micropolar blood flow through an elastic artery has been studied. An Arbitrary Lagrangian-Eulerian (ALE) formulation of the dominate equations have been produced to model the fully-coupled Fluid-Structure Interaction (FSI). Furthermore, those derived equations have also been numerically dealt with using finite difference scheme through exploiting a mesh generation technique which leads to a uniformly spaced grid in the computational plane. The effect of variations in cardiac output and elastic modulus of artery wall on blood pressure has been determined by utilizing blood-pressure regulating drugs like Atenolol. Also a numerical model has been prepared in order to precisely define and verify the effects of various dosage of a drug on blood flow in arteries without resorting to the inefficient prevalent experiments that could have many mistakes and costs. The numerical results have shown that the artery wall stiffness has been decreased about 29 % by Atenolol dose between 0 and 0.02 mg/kg and have a blood pressure increment between 0.02 and 0.04 mg/kg.

Conference Title : Seventh International Conference On Advances in Mechanical, Aeronautical and Production Techniques - MAPT 2017
Conference Date(s) : 01-02 July, 2017
Place : G Tower Hotel, Kuala Lumpur, Malaysia
No fo Author(s) : 3
DOI : 10.15224/978-1-63248-129-0-42
Page(s) : 5 - 9
Electronic ISBN : 978-1-63248-129-0
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