Second International Conference on Advances in Bio-Informatics and Environmental Engineering - ICABEE 2015
Author(s) : CORINNE RAVELET, ERIC DAUSSE, ERIC PEYRIN, GUILLAUME DURAND, JEAN-JACQUES TOULME
We developed biosensors in which the detection element is an oligonucleotide -an aptamer- obtained through a combinatorial process. We characterized aptamers specific for different biomarkers. They can be integrated into different devices, allowing their use either in a grafted format or in solution. We developped a multiplex assay signaling the presence of nucleoside derivatives by either surface plasmon resonance or fluorescence anisotropy.