Conference Proceedings

International Conference on Advances in Computer and Information Technology - ACIT 2013

VEDEPSO Algorithm for Designing Unique Library of DNA Strands

Author(s) : KRISHNA VENI SELVAN, MOHD SAUFEE MUHAMMAD, SHARIFAH MASNIAH WAN MASRA

Abstract

Combinatorial optimization happens when there are two or more objectives to be optimized in solving a problem. The DNA words or oligonucleotides designing are one of a multi-objective combinatorial optimization problem. In this paper, the designations implied minimizations of H-measure, similarity, hairpin and continuity functions subjected to a predefine range of melting temperature and GC-content. A novel multi-swarm optimization approach is introduced to design a library of DNA strands. This approach is called vector evaluated differential evolution particle swarm optimization (VEDEPSO). The results obtained from the VEDEPSO algorithm is evaluated using Pareto dominance technique. A list of selected non-dominated solutions is shown as the final results from the research.

Conference Title : International Conference on Advances in Computer and Information Technology - ACIT 2013
Conference Date(s) : May 04-05, 2013
Place : Hotel Shangri-La, Kuala Lumpur, Malaysia
No fo Author(s) : 3
DOI : 10.15224/978-981-07-6261-2-08
Page(s) : 38 - 41
Electronic ISBN : 978-981-07-6261-2
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